Pharmaceutical Intermediates

Pentafluoropentanol CAS:148043-73-6 98%min

Chemical Name:4,4,5,5,5-Pentafluoro-1-pentanol
CAS.NO:148043-73-6
Synonyms:4,4,5,5,5-Pentafluoro-1-pentanol;4,4,5,5,5-pentafluoropentanol;Pentafluoropentanol
Molecular Formula:C5H7F5O
Molecular Weight:178.100
Physical and Chemical Properties:
Density:1.350;
Boiling point:62-64oC;
Melting point:236oC;
Index of Refraction:1.327;
 
Specification:
Appearance:Colorless to pale yellow liquid
Assay:≥98%
Total impurity:≤2.0%
 
Description:
The downstream products are 4,4,5,5,5-Pentafluoro-1-pentanethiol
For the treatment of metastatic breast cancer treatment drug Fulvestrant, Fulvestrant intermediates
 
Free radical reaction with pentafluoroiodoethane and propenol as 4,4,5,5,5-pentafluoro-2- Iodine-1-pentanol. Dehalogenation reaction under the action of reducing agent to form pentafluoropentanol.

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